CD74 Protein, Human, Recombinant (His) V2

Name: CD74 Protein, Human, Recombinant (His) V2
Brand: TargetMol
SKU: TMPY-01199U
Rating: 4.5 (1 reviews)

(Synonyms: II, Ia-γ, Ia-GAMMA, HLADG, DHLAG, CD74 molecule, major histocompatibility complex, class II invariant chain) Copy Product Info

Synonyms: II, Ia-γ, Ia-GAMMA, HLADG, DHLAG, CD74 molecule, major histocompatibility complex, class II invariant chain

Catalog No. TMPY-01199U Copy Product Info

CD74 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is NP_004346.1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$47	7-10 days	7-10 days
10 µg	$72	7-10 days	7-10 days
20 µg	$116	7-10 days	7-10 days
50 µg	$223	7-10 days	7-10 days
100 µg	$373	7-10 days	7-10 days
200 µg	$659	7-10 days	7-10 days
500 µg	Preferential	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human CD74 at 0.5 μg/ml (100 μl/Well) on the plate. Dose response curve for Anti-CD74 Antibody, hFc Tag with the EC50 of 8.9 ng/ml determined by ELISA.
Description	CD74 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is NP_004346.1.
Species	Human
Expression System	HEK293 Cells
Tag	N-His
Accession Number	NP_004346.1
Construction	Gln73-Met232
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	II, Ia-γ, Ia-GAMMA, HLADG, DHLAG, CD74 molecule, major histocompatibility complex, class II invariant chain
Research Background	CD74 (invariant MHC class II) regulates protein trafficking and is a receptor for macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT/MIF-2). CD74 expression is increased in tubular cells and/or glomerular podocytes and parietal cells in human metabolic nephropathies, polycystic kidney disease, graft rejection and kidney cancer and in experimental diabetic nephropathy and glomerulonephritis.

Chemical Properties

Molecular Weight

19.1 kDa (Predicted); 30-40 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.