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Anti-Trefoil factor 1 Antibody (4N658)
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Catalog No. TMAB-13751
Anti-Trefoil factor 1 Antibody (4N658) is a Rabbit antibody targeting Trefoil factor 1. Anti-Trefoil factor 1 Antibody (4N658) can be used in IHC-P,WB,IHC-Fr,IF,FCM,ICC/IF.
Anti-Trefoil factor 1 Antibody (4N658)
Anti-Trefoil factor 1 Antibody (4N658)
😃Good
Catalog No. TMAB-13751
Anti-Trefoil factor 1 Antibody (4N658) is a Rabbit antibody targeting Trefoil factor 1. Anti-Trefoil factor 1 Antibody (4N658) can be used in IHC-P,WB,IHC-Fr,IF,FCM,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Trefoil factor 1 Antibody (4N658) is a Rabbit antibody targeting Trefoil factor 1. Anti-Trefoil factor 1 Antibody (4N658) can be used in IHC-P,WB,IHC-Fr,IF,FCM,ICC/IF. |
| Ig Type | IgG |
| Clone | 4N658 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; WB: 1:500-2000; IHC-Fr: 1:50-200; IF: 1:50-200; FCM: 1:50-100; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | TBS (pH7.4), 1% BSA, 40% Glycerol and 0.02% Proclin300. |
| Concentration | 1mg/ml |
| Research Background | Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]. |
| Immunogen | A synthesized peptide: human Trefoil factor 1 |
| Antigen Species | Human |
| Gene Name | TFF1 |
| Gene ID | |
| Protein Name | Trefoil factor 1 |
| Uniprot ID | |
| Function | Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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