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Anti-ATF5 Antibody (1S976) is a Rabbit antibody targeting ATF5. Anti-ATF5 Antibody (1S976) can be used in FCM, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
| Description | Anti-ATF5 Antibody (1S976) is a Rabbit antibody targeting ATF5. Anti-ATF5 Antibody (1S976) can be used in FCM, IP, WB. |
| Ig Type | IgG |
| Clone | 1S976 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | FCM=1:50-100; IP=1:20-50; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic and Nuclear |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.Important regulator of the cerebral cortex formation, functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons. Must be down-regulated in order for such cells to exit the cycle and differentiate.Participates in the pathways by which SHH promotes cerebellar granule neuron progenitor cells proliferation. |
| Immunogen | A synthesized peptide: human ATF5 |
| Antigen Species | Human |
| Gene Name | ATF5 |
| Gene ID | |
| Protein Name | Cyclic AMP-dependent transcription factor ATF-5 |
| Uniprot ID | |
| Function | ATF5 or Activating transcription factor 5, binds to cAMP inducible promoters and is involved in gene transcription. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF5 plays a role in inhibition of nerve growth factor induced neuronal outgrowth and regulation of neurogenesis. |
| Molecular Weight | Theoretical: 31 kDa. Actual: 31 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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