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Anti-CRCP Antibody (7A447)

Catalog No. TMAB-04640 Copy Product Info
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Anti-CRCP Antibody (7A447) is a Rabbit antibody targeting CRCP. Anti-CRCP Antibody (7A447) can be used in WB,IHC-P,IHC-Fr,IF,IP.

Anti-CRCP Antibody (7A447)

Copy Product Info
🥰Excellent
Catalog No. TMAB-04640

Anti-CRCP Antibody (7A447) is a Rabbit antibody targeting CRCP. Anti-CRCP Antibody (7A447) can be used in WB,IHC-P,IHC-Fr,IF,IP.

Anti-CRCP Antibody
(7A447)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CRCP Antibody (7A447) is a Rabbit antibody targeting CRCP. Anti-CRCP Antibody (7A447) can be used in WB,IHC-P,IHC-Fr,IF,IP.
Ig Type
IgG
Clone
7A447
Reactivity
Human,Mouse (predicted:Rat)
Verified Activity
1. 25 μg total protein per lane of various lysates (see on figure) probed with CRCP monoclonal antibody, unconjugated (TMAB-04640) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Prostate Tumor; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CRCP Monoclonal Antibody, Unconjugated (TMAB-04640) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CRCP Monoclonal Antibody, Unconjugated (TMAB-04640) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CRCP Monoclonal Antibody, Unconjugated (TMAB-04640) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining.
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cell membrane.
Tissue SpecificityUbiquitous. Most prevalent in testis.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Antigen Details
Immunogen
A synthesized peptide: human CRCP
Antigen Species
Human
Gene Name
CRCP
Gene ID
Protein Name
DNA-directed RNA polymerase III subunit RPC9
Uniprot ID
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
Chemical Properties
Molecular WeightTheoretical: 17 kDa. Actual: 22 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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