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Anti-mGluR2 Antibody (4I792) is a Rabbit antibody targeting mGluR2. Anti-mGluR2 Antibody (4I792) can be used in WB,ICC/IF,IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-mGluR2 Antibody (4I792) is a Rabbit antibody targeting mGluR2. Anti-mGluR2 Antibody (4I792) can be used in WB,ICC/IF,IHC. |
Synonyms | OTTHUMP00000210986, OTTHUMP00000210984, mGluR 2, mGlu2, Metabotropic glutamate receptor 2, GRM2_HUMAN, GRM2, GPRC1B, Glutamate receptor metabotropic 2, Glutamate receptor homolog, Glutamate metabotropic receptor 2, GLURB, GLUR2, AMPA selective glutamate receptor 2 |
Ig Type | IgG |
Clone | 4I792 |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-mGluR2 antibody. Counter stained with hematoxylin. 2. ICC staining mGluR2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining mGluR2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining mGluR2 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
Application | |
Recommended Dose | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-2, which may interact with GRASP, acts as a receptor for glutamate. It may also be involved in the regulation of neurotransmission suppression and in synaptogenesis or synaptic stablization. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 96 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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