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Anti-Her2/ERBB2 Antibody (5S123) (Synonyms: erb-b2 receptor tyrosine kinase 2, EGFR2)

Catalog No. TMAY-00035 Copy Product Info
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Anti-Her2/ERBB2 Antibody (5S123) is a Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody (5S123) can be used in FCM.

Anti-Her2/ERBB2 Antibody (5S123)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00035
Synonyms erb-b2 receptor tyrosine kinase 2, EGFR2

Anti-Her2/ERBB2 Antibody (5S123) is a Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody (5S123) can be used in FCM.

Anti-Her2/ERBB2 Antibody
(5S123)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Her2/ERBB2 Antibody (5S123) is a Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody (5S123) can be used in FCM.
Synonymserb-b2 receptor tyrosine kinase 2, EGFR2
Ig Type
Mouse IgG1
Clone
5S123
Reactivity
Human
Specificity
Human Her2/ERBB2
Has cross-reactivity in ELISA with
Human HER2 / ErbB2 (ECD,1-652)
Human HER2 / ErbB2 (ECD,1-652) (His Tag)
Human HER2 / ErbB2 (ECD, domain IV) (His Tag)
Human HER2 / ErbB2 (Cytoplasmic Domain, 676-1255) (His & GST Tag)
Verified Activity
Flow cytometric analysis of anti-Human ErbB2 on SKBR3 cells.
Application
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundHuman epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Human Her2 / ERBB2 Protein (TMPY-01137)
Antigen Species
Human
Biology Area
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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