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Anti-Cytokeratin 8 Antibody (7D171)

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Catalog No. TMAB-04962

Anti-Cytokeratin 8 Antibody (7D171) is a Rabbit antibody targeting Cytokeratin 8. Anti-Cytokeratin 8 Antibody (7D171) can be used in WB,IHC-Fr,ICC/IF,IF,IHC-P.

Anti-Cytokeratin 8 Antibody (7D171)

Anti-Cytokeratin 8 Antibody (7D171)

😃Good
Catalog No. TMAB-04962
Anti-Cytokeratin 8 Antibody (7D171) is a Rabbit antibody targeting Cytokeratin 8. Anti-Cytokeratin 8 Antibody (7D171) can be used in WB,IHC-Fr,ICC/IF,IF,IHC-P.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Cytokeratin 8 Antibody (7D171) is a Rabbit antibody targeting Cytokeratin 8. Anti-Cytokeratin 8 Antibody (7D171) can be used in WB,IHC-Fr,ICC/IF,IF,IHC-P.
Ig Type
IgG
Clone
7D171
Reactivity
Human,Mouse,Rat
Application
WB
IHC-Fr
ICC/IF
IF
IHC-P
Recommended Dose
WB: 1:1000-5000; IHC-Fr: 1:200-800; ICC/IF: 1:100-500; IF: 1:200-800; IHC-P: 1:200-800
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
Tissue SpecificityObserved in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
Antigen Details
Immunogen
A synthesized peptide: human Cytokeratin 8
Antigen Species
Human
Gene Name
KRT8
Gene ID
3856
Protein Name
Keratin, type II cytoskeletal 8
Uniprot ID
P05787
Function
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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