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Anti-ADRB2 Antibody (1U719)

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Catalog No. TMAB-02360

Anti-ADRB2 Antibody (1U719) is a Rabbit antibody targeting ADRB2. Anti-ADRB2 Antibody (1U719) can be used in IHC-P,IHC-Fr,IF.

Anti-ADRB2 Antibody (1U719)

Anti-ADRB2 Antibody (1U719)

😃Good
Catalog No. TMAB-02360
Anti-ADRB2 Antibody (1U719) is a Rabbit antibody targeting ADRB2. Anti-ADRB2 Antibody (1U719) can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ADRB2 Antibody (1U719) is a Rabbit antibody targeting ADRB2. Anti-ADRB2 Antibody (1U719) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
1U719
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein. Note=Colocalizes with VHL at the cell membrane.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundBeta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.
Antigen Details
Immunogen
A synthesized peptide: human beta 2 Adrenergic receptor
Antigen Species
Human
Gene Name
ADRB2
Gene ID
Protein Name
beta-2 adrenergic receptor
Uniprot ID
Function
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Chemical Properties
Molecular WeightTheoretical: 60 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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