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Anti-5HT2C Receptor Antibody (7D349)
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Catalog No. TMAB-02106
Alias Serotonin receptor 2C, Serotonin 5-HT-2C receptor, serotonin 2c receptor, serotonin 1c receptor, HTR2C, Htr1c, 5-hydroxytryptamine(serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 1C, 5Hydroxytryptamine 2C receptor, 5-HTR2C, 5HTR2C, 5HT2C_HUMAN, 5-HT-2C, 5-HT2C, 5HT2C, 5-ht-1c receptor, 5-HT-1C, 5-HT1C, 5HT1C, 5 Hydroxytryptamine 2C receptor
Anti-5HT2C Receptor Antibody (7D349) is a Rabbit antibody targeting 5HT2C Receptor. Anti-5HT2C Receptor Antibody (7D349) can be used in WB.
Anti-5HT2C Receptor Antibody (7D349)
Anti-5HT2C Receptor Antibody (7D349)
Copy Product Info😃Good
Catalog No. TMAB-02106Alias Serotonin receptor 2C, Serotonin 5-HT-2C receptor, serotonin 2c receptor, serotonin 1c receptor, HTR2C, Htr1c, 5-hydroxytryptamine(serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 1C, 5Hydroxytryptamine 2C receptor, 5-HTR2C, 5HTR2C, 5HT2C_HUMAN, 5-HT-2C, 5-HT2C, 5HT2C, 5-ht-1c receptor, 5-HT-1C, 5-HT1C, 5HT1C, 5 Hydroxytryptamine 2C receptor
Anti-5HT2C Receptor Antibody (7D349) is a Rabbit antibody targeting 5HT2C Receptor. Anti-5HT2C Receptor Antibody (7D349) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-5HT2C Receptor Antibody (7D349) is a Rabbit antibody targeting 5HT2C Receptor. Anti-5HT2C Receptor Antibody (7D349) can be used in WB. |
| Synonyms | Serotonin receptor 2C, Serotonin 5-HT-2C receptor, serotonin 2c receptor, serotonin 1c receptor, HTR2C, Htr1c, 5-hydroxytryptamine(serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 1C, 5Hydroxytryptamine 2C receptor, 5-HTR2C, 5HTR2C, 5HT2C_HUMAN, 5-HT-2C, 5-HT2C, 5HT2C, 5-ht-1c receptor, 5-HT-1C, 5-HT1C, 5HT1C, 5 Hydroxytryptamine 2C receptor |
| Ig Type | IgG |
| Clone | 7D349 |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with 5HT2C Receptor monoclonal antibody, unconjugated (TMAB-02106) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008]. |
| Immunogen | A synthesized peptide: human 5 HT2C |
| Antigen Species | Human |
| Gene Name | HTR2C |
| Gene ID | |
| Protein Name | 5-hydroxytryptamine receptor 2C |
| Uniprot ID | |
| Function | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Molecular Weight | Theoretical: 52 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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