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Anti-SAE2/UBA2 Antibody (4K320)

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Catalog No. TMAB-12474

Anti-SAE2/UBA2 Antibody (4K320) is a Rabbit antibody targeting SAE2/UBA2. Anti-SAE2/UBA2 Antibody (4K320) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.

Anti-SAE2/UBA2 Antibody (4K320)

Anti-SAE2/UBA2 Antibody (4K320)

Copy Product Info
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Catalog No. TMAB-12474
Anti-SAE2/UBA2 Antibody (4K320) is a Rabbit antibody targeting SAE2/UBA2. Anti-SAE2/UBA2 Antibody (4K320) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SAE2/UBA2 Antibody (4K320) is a Rabbit antibody targeting SAE2/UBA2. Anti-SAE2/UBA2 Antibody (4K320) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Ig Type
IgG
Clone
4K320
Reactivity
Human (predicted:Mouse,Rat)
Verified Activity
25 ug total protein per lane of various lysates (see on figure) probed with SAE2/UBA2 monoclonal antibody, unconjugated (TMAB-12474) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:100-200; IHC-P=1:100-200; IP=1:20-50; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundThe heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Antigen Details
Immunogen
A synthesized peptide: human UBA2
Antigen Species
Human
Gene Name
UBA2
Gene ID
Protein Name
SUMO-activating enzyme subunit 2
Uniprot ID
Function
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Chemical Properties
Molecular WeightTheoretical: 71 kDa. Actual: 90 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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