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Anti-BCL6 Antibody (4B197)
😃Good
Catalog No. TMAC-00401
Alias ZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6
Anti-BCL6 Antibody (4B197) is a Rabbit antibody targeting BCL6. Anti-BCL6 Antibody (4B197) can be used in WB.
Anti-BCL6 Antibody (4B197)
Anti-BCL6 Antibody (4B197)
😃Good
Catalog No. TMAC-00401Alias ZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6
Anti-BCL6 Antibody (4B197) is a Rabbit antibody targeting BCL6. Anti-BCL6 Antibody (4B197) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-BCL6 Antibody (4B197) is a Rabbit antibody targeting BCL6. Anti-BCL6 Antibody (4B197) can be used in WB. |
| Synonyms | ZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6 |
| Ig Type | IgG |
| Clone | 4B197 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of Bcl-6 on NIH-3T3 cell lysate using anti-Bcl-6 antibody at 1/500 dilution.  |
| Application | |
| Recommended Dose | WB: 1:1000-5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and Th1/Th2 differentiation. Bcl-6 negatively regulates NFkB expression, thereby inhibiting NFkB-mediated cellular functions. HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs). Bcl-6 is frequently deregulated in non-Hodgkin's B cell lymphomas. The human BCL6 gene has been shown to encode a protein of 706 amino acids. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 79 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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