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Anti-Cortactin Antibody (9I917)

(Synonyms: SRC8_HUMAN, Src substrate cortactin, p80/85 src substrate, Oncogene EMS1, Mammary tumor and squamous cell carcinoma associated, FLJ34459, EMS1, EMS 1, CTTN, Amplaxin) Copy Product Info
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Synonyms: SRC8_HUMAN, Src substrate cortactin, p80/85 src substrate, Oncogene EMS1, Mammary tumor and squamous cell carcinoma associated, FLJ34459, EMS1, EMS 1, CTTN, Amplaxin

Catalog No. TMAC-00941 Copy Product Info
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Anti-Cortactin Antibody (9I917) is a Rabbit antibody targeting Cortactin. Anti-Cortactin Antibody (9I917) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-Cortactin Antibody
(9I917)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Cortactin Antibody (9I917) is a Rabbit antibody targeting Cortactin. Anti-Cortactin Antibody (9I917) can be used in FCM,ICC/IF,IHC,IP,WB.
SynonymsSRC8_HUMAN, Src substrate cortactin, p80/85 src substrate, Oncogene EMS1, Mammary tumor and squamous cell carcinoma associated, FLJ34459, EMS1, EMS 1, CTTN, Amplaxin
Ig Type
IgG
Clone
9I917
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCortactin (also designated Ems-1) is a filamentous Actin (F-Actin) binding protein that has been shown to be a substrate for Src p60. Cortactin contains tandem 37 amino acid repeats at the amino-terminus and an SH3 domain at the carboxy-terminus. The tandem repeats appear to be necessary for F-Actin binding. Tyrosine phosphorylation of Cortactin by Src p60 results in diminished F-Actin binding to Cortactin and reduced F-Actin cross-linking activity. Cortactin has also been shown to be phosphorylated in response to FGF-1. Cortactin exhibits abundant expression in megakaryocytes and platelets, and it may play a role in the maturation of megakaryocytes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 75 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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