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Anti-BDKRB2 Antibody (4Y573) (Synonyms: Kinin B2 Bradykinin receptor beta 2, DKFZp686O088, BRB2, BRB 2, Brad...)

Catalog No. TMAC-00411 Copy Product Info
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Anti-BDKRB2 Antibody (4Y573) is a Rabbit antibody targeting BDKRB2. Anti-BDKRB2 Antibody (4Y573) can be used in FCM,IP,WB.

Anti-BDKRB2 Antibody (4Y573)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00411
Synonyms Kinin B2 Bradykinin receptor beta 2, DKFZp686O088, BRB2, BRB 2, Bradykinin receptor beta 2, Bradykinin receptor b2, BR B2, BKR2, BKR 2, BK2R, BK2 receptor, BK2, BK R2, BK 2 receptor, BK 2, BDKRB 2, BDKR B2, B2R, B2BRA, B2BKR, B2 bradykinin receptor, B2

Anti-BDKRB2 Antibody (4Y573) is a Rabbit antibody targeting BDKRB2. Anti-BDKRB2 Antibody (4Y573) can be used in FCM,IP,WB.

Anti-BDKRB2 Antibody
(4Y573)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BDKRB2 Antibody (4Y573) is a Rabbit antibody targeting BDKRB2. Anti-BDKRB2 Antibody (4Y573) can be used in FCM,IP,WB.
SynonymsKinin B2 Bradykinin receptor beta 2, DKFZp686O088, BRB2, BRB 2, Bradykinin receptor beta 2, Bradykinin receptor b2, BR B2, BKR2, BKR 2, BK2R, BK2 receptor, BK2, BK R2, BK 2 receptor, BK 2, BDKRB 2, BDKR B2, B2R, B2BRA, B2BKR, B2 bradykinin receptor, B2
Ig Type
IgG
Clone
4Y573
Reactivity
Human,Mouse
Verified Activity
1. Western blot analysis of BDKRB2 on MCF-7 cell lysate using anti-BDKRB2 antibody at 1/500 dilution.
2. Flow cytometric analysis of SH-SY5Y cells with BDKRB2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IP: 1:10-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundKinins are important biologically active peptides that mediate cardiovascular homeostasis, inflammation and nociception. Bradykinin, the major effector peptide of the kallikrein-kinin system, is regulated by angiotensin-converting enzyme (ACE), which degrades the peptide. Bradykinin normally exerts its effects through the activation of two seven transmembrane G-protein coupled receptors, named B1 and B2. The B2 receptor is constitutively expressed and preferentially binds full length bradykinin. Deletion of the B2 receptor leads to salt-sensitive hypertension and altered nociception in mice. The B1 receptor binds to derivatives of bradykinin and kallidin, which are produced by carboxypeptidase action to generate the products des-Arg9-bradykinin and des-Arg10-kallidin, respectively. The expression of the B1 receptor is inducible by inflammatory mediators, such as bacterial lipopolysaccharide (LPS) and cytokines. The B1 and B2 receptors represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 80 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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