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Anti-PPAR gamma Antibody (5H73)
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Catalog No. TMAB-11653
Anti-PPAR gamma Antibody (5H73) is a Rabbit antibody targeting PPAR gamma. Anti-PPAR gamma Antibody (5H73) can be used in WB,FCM,ICC/IF.
Anti-PPAR gamma Antibody (5H73)
Anti-PPAR gamma Antibody (5H73)
😃Good
Catalog No. TMAB-11653
Anti-PPAR gamma Antibody (5H73) is a Rabbit antibody targeting PPAR gamma. Anti-PPAR gamma Antibody (5H73) can be used in WB,FCM,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PPAR gamma Antibody (5H73) is a Rabbit antibody targeting PPAR gamma. Anti-PPAR gamma Antibody (5H73) can be used in WB,FCM,ICC/IF. |
| Ig Type | IgG |
| Clone | 5H73 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-100; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nuclear |
| Tissue Specificity | Skeletal muscle, liver, heart and kidney. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide: human PPAR gamma |
| Antigen Species | Human |
| Gene Name | PPARG |
| Gene ID | |
| Protein Name | Peroxisome proliferator-activated receptor gamma |
| Uniprot ID | |
| Function | Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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