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Anti-DGCR8 Antibody (8J740) is a Rabbit antibody targeting DGCR8. Anti-DGCR8 Antibody (8J740) can be used in WB,ICC/IF,IP.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-DGCR8 Antibody (8J740) is a Rabbit antibody targeting DGCR8. Anti-DGCR8 Antibody (8J740) can be used in WB,ICC/IF,IP. |
Synonyms | pasha, Microprocessor complex subunit DGCR8, Gy1, DiGeorge syndrome critical region gene 8, DiGeorge syndrome critical region 8, DGCRK 6, DGCR8 microprocessor complex subunit, DGCR 8, D16Wis2, D16H22S788E, C22orf12 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of DGCR8 on different lysates using anti-DGCR8 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: PC12, Lane 3: NIH/3T3. 2. ICC staining DGCR8 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining DGCR8 in PC12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
Application | |
Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | DGS8, also designated DiGeorge syndrome critical region 8 protein, plays a role in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS). It is a ubiquitously expressed protein encoded by the gene DGCR8, which is deleted in DiGeorge syndrome. DiGeorge syndrome is characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. In mouse, DGS8 is detected primarily in embryonic brain, vessels, thymus and palate. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 100 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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