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Anti-HBEGF Antibody (2V361)

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Catalog No. TMAB-06902

Anti-HBEGF Antibody (2V361) is a Rabbit antibody targeting HBEGF. Anti-HBEGF Antibody (2V361) can be used in WB.

Anti-HBEGF Antibody (2V361)

Anti-HBEGF Antibody (2V361)

😃Good
Catalog No. TMAB-06902
Anti-HBEGF Antibody (2V361) is a Rabbit antibody targeting HBEGF. Anti-HBEGF Antibody (2V361) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HBEGF Antibody (2V361) is a Rabbit antibody targeting HBEGF. Anti-HBEGF Antibody (2V361) can be used in WB.
Ig Type
IgG
Clone
2V361
Reactivity
Human,Rat
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationHeparin-binding EGF-like growth factor: Secreted, extracellular space. Note=Mature HB-EGF is released into the extracellular space and probably binds to a receptor.Proheparin-binding EGF-like growth factor: Cell membrane; Single-pass type I membrane protein.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundGrowth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Antigen Details
Immunogen
A synthesized peptide: human HB EGF
Antigen Species
Human
Gene Name
HBEGF
Gene ID
1839
Protein Name
Proheparin-binding EGF-like growth factor
Uniprot ID
Q99075
Function
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Chemical Properties
Molecular WeightTheoretical: 23 kDa. Actual: 23 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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