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Anti-Integin alpha 3 Antibody (2W405)
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Catalog No. TMAB-07734
Anti-Integin alpha 3 Antibody (2W405) is a Mouse antibody targeting Integin alpha 3. Anti-Integin alpha 3 Antibody (2W405) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Integin alpha 3 Antibody (2W405)
Anti-Integin alpha 3 Antibody (2W405)
Copy Product Info😃Good
Catalog No. TMAB-07734
Anti-Integin alpha 3 Antibody (2W405) is a Mouse antibody targeting Integin alpha 3. Anti-Integin alpha 3 Antibody (2W405) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-Integin alpha 3 Antibody (2W405) is a Mouse antibody targeting Integin alpha 3. Anti-Integin alpha 3 Antibody (2W405) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1, Kappa |
| Clone | 2W405 |
| Reactivity | Human (predicted:Mouse) |
| Verified Activity | 1. Tissue: Human adenocarcinoma Section type: Formalin fixed & Paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:100 Primary ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Comment: Color brown is the positive signal for TMAB-07734 2. Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: 4°C overnight Lysate: HeLa, C2C12 Protein loading quantity: 20 μg Exposure time: 30 s Predicted MW: 120 kDa Observed MW: 130 kDa 3. Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:5000 Primary ab incubation condition: 4°C overnight Lysate: A549 Protein loading quantity: 20 μg Exposure time: 30 s Predicted MW: 120 kDa Observed MW: 130 kDa |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells. |
| Construction | Recombinant Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008] |
| Gene Name | ITGA3 |
| Gene ID | |
| Protein Name | Integrin alpha-3 |
| Function | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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