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Anti-BCL2 Antibody (9S932)
(Synonyms: PPP1R50, Bcl-2, B-cell CLL/lymphoma 2) Copy Product Info
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Synonyms: PPP1R50, Bcl-2, B-cell CLL/lymphoma 2
Catalog No. TMAC-00393 Copy Product Info
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Anti-BCL2 Antibody (9S932) is a Rabbit antibody targeting BCL2. Anti-BCL2 Antibody (9S932) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-BCL2 Antibody
(9S932)
(9S932)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-BCL2 Antibody (9S932) is a Rabbit antibody targeting BCL2. Anti-BCL2 Antibody (9S932) can be used in FCM,ICC/IF,IHC,IP,WB. |
| Synonyms | PPP1R50, Bcl-2, B-cell CLL/lymphoma 2 |
| Ig Type | IgG |
| Clone | 9S932 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-500; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Apoptosis is defined as a set of cascades which, when initiated, programs the cell to undergo lethal changes such as membrane blebbing, mitochondrial break down and DNA fragmentation. Bcl-2 is one among many key regulators of apoptosis, which are essential for proper development, tissue homeostasis, and protection against foreign pathogens. Human Bcl-2 is an apoptotic, membrane-associated oncoprotein that can promote cell survival through protein-protein interactions with other Bcl-2 related family members, such as the death suppressors Bcl-xl, Mcl-1, Bcl-w, and A1 or the death agonists Bax, Bak, Bik, Bad, and Bid. The apoptotic function of Bcl-2 can also be regulated through proteolytic processing and phospho-rylation. Bcl-2 may promote cell survival by interfering with the activation of the cytochrome c/Apaf-1 pathway through stabilization of the mitochondrial membrane. Mutations in the Bcl-2 gene can contribute to cancers where normal physiological cell death mechanisms are compromised by deregulation of the apoptotic influence of Bcl-2. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 26/22 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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