Immobilized Human Fas Ligand, His Tag at 2 μg/ml (100 μl/Well) on the plate. Dose response curve for Human Fas, hFc Tag with the EC50 of 0.19 μg/ml determined by ELISA (QC Test).
Human Fas, His Tag immobilized on CM5 Chip can bind Human Fas Ligand, His Tag with an affinity constant of 19.45 nM as determined in SPR assay (Biacore T200).

Fas Ligand Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is AAH17502.1.

Human

HEK293 Cells

TNLG1A,TNFSF6,FASLG,FASL,Fas ligand,CD95-L,CD95L,CD178,APTL,APT1LG1,ALPS1B

Pro134-Leu281

> 95% as determined by Tris-Bis PAGE

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Fas ligand (FasL, CD95L) is a 40-kDa type II transmembrane protein that binds to Fas (CD95) receptors and promotes programmed cell death. Fas receptors are expressed at higher levels in many tumors than in normal cells.Somewhat paradoxically, elimination of Fas or FasL from tumors also leads to death induced by CD95 receptor/ligand elimination (DICE).