Human IL-3 R Beta, His Tag immobilized on CM5 Chip can bind Human GM-CSF, No Tag with an affinity constant of 4.13 μM as determined in SPR assay (Biacore T200) (QC Test).

CD131 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P32927-1.

Human

HEK293 Cells

Thr17-Trp443

> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Interleukin-3 receptor (IL-3R) is a heterodimer that comprises an IL-3 specific alpha chain (IL-3R alpha) and a common beta chain (beta C) that is shared with the receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-5. The beta c subunit does not bind any cytokine by itself but is involved in the formation of high-affinity functional receptors for IL-5 and GM-CSF. These receptors belong to the cytokine receptor superfamily, but they are structurally and functionally more related to each other and thus make up a distinct subfamily.