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Anti-Biglycan Antibody (9V222)
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Catalog No. TMAC-00434
Alias SLRR1A, PG-S1, PGI, DSPG1, biglycan
Anti-Biglycan Antibody (9V222) is a Rabbit antibody targeting Biglycan. Anti-Biglycan Antibody (9V222) can be used in WB,IHC,FCM,IP.
Anti-Biglycan Antibody (9V222)
Anti-Biglycan Antibody (9V222)
😃Good
Catalog No. TMAC-00434Alias SLRR1A, PG-S1, PGI, DSPG1, biglycan
Anti-Biglycan Antibody (9V222) is a Rabbit antibody targeting Biglycan. Anti-Biglycan Antibody (9V222) can be used in WB,IHC,FCM,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-Biglycan Antibody (9V222) is a Rabbit antibody targeting Biglycan. Anti-Biglycan Antibody (9V222) can be used in WB,IHC,FCM,IP. |
| Synonyms | SLRR1A, PG-S1, PGI, DSPG1, biglycan |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of Biglycan on mouse heart and human skin tissue lysates using anti-Biglycan antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-Biglycan antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Biglycan antibody. Counter stained with hematoxylin. 4. Flow cytometric analysis of HepG2 cells with Biglycan antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Biglycan, a class I small leucine rich proteoglycan (SLRP) present in the extracellular matrix, influences bone cell differentiation and proliferation. Biglycan contains two chondroitin sulfate glucosaminoglycan (GAG) chains attached near its amino terminus, whereas a closely related SLRP, decorin, contains only one. Biglycan deficient specimens possess diminished capacity to produce bone cells precursors, a lessened response to TGFβ, reduced collagen synthesis, and increased apoptosis. Patients with rheumatoid arthritis express increased immunity to biglycan whereas osteoarthritis patients do not, suggesting that higher immunity to SLRPs may play a role in the pathogenesis of inflammatory rheumatic diseases. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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