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Anti-Histone H1.0 Antibody (8J775)

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Catalog No. TMAB-07057

Anti-Histone H1.0 Antibody (8J775) is a Rabbit antibody targeting Histone H1.0. Anti-Histone H1.0 Antibody (8J775) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.

Anti-Histone H1.0 Antibody (8J775)

Anti-Histone H1.0 Antibody (8J775)

😃Good
Catalog No. TMAB-07057
Anti-Histone H1.0 Antibody (8J775) is a Rabbit antibody targeting Histone H1.0. Anti-Histone H1.0 Antibody (8J775) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Histone H1.0 Antibody (8J775) is a Rabbit antibody targeting Histone H1.0. Anti-Histone H1.0 Antibody (8J775) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
8J775
Reactivity
Human,Mouse,Rat
Application
FCM
ICC/IF
IF
IHC-Fr
IHC-P
WB
Recommended Dose
FCM=1:50-100; ICC/IF=1:100-200; IF=1:200-1000; IHC-Fr=1:200-1000; IHC-P=1:200-1000; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Chromosome.
Tissue SpecificityOocyte-specific.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
Antigen Details
Immunogen
A synthesized peptide: human Histone H1.0
Antigen Species
Human
Gene Name
H1-0
Gene ID
3005
Protein Name
Histone H1.0
Uniprot ID
P07305
Function
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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