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Anti-DOK1 Antibody (9G208)

Catalog No. TMAB-05277 Copy Product Info
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Anti-DOK1 Antibody (9G208) is a Rabbit antibody targeting DOK1. Anti-DOK1 Antibody (9G208) can be used in WB,ICC/IF.

Anti-DOK1 Antibody (9G208)

Copy Product Info
🥰Excellent
Catalog No. TMAB-05277

Anti-DOK1 Antibody (9G208) is a Rabbit antibody targeting DOK1. Anti-DOK1 Antibody (9G208) can be used in WB,ICC/IF.

Anti-DOK1 Antibody
(9G208)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DOK1 Antibody (9G208) is a Rabbit antibody targeting DOK1. Anti-DOK1 Antibody (9G208) can be used in WB,ICC/IF.
Ig Type
IgG
Clone
9G208
Reactivity
Human,Mouse,Rat
Verified Activity
Western blot analysis of K562 cell lysate. Using DOK1 (TMAB-05277) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:1000-2000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationIsoform 1: Cytoplasm. Isoform 3: Cytoplasm, perinuclear region.
Tissue SpecificityExpressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundDOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Antigen Details
Immunogen
A synthesized peptide: human DOK1
Antigen Species
Human
Gene Name
DOK1
Gene ID
Protein Name
Docking protein 1
Uniprot ID
Function
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Chemical Properties
Molecular WeightTheoretical: 52 kDa. Actual: 65 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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