Immobilized Mouse GAS6, His Tag at 5 μg/m l (100 μl/well) on the plate. Dose response curve for Human AXL, hFc Tag with the EC50 of 3.1 ng/ml determined by ELISA (QC Test).
Mouse AXL, His Tag immobilized on CM5 Chip can bind Mouse GAS6, His Tag with an affinity constant of 15.62 nM as determined in SPR assay (Biacore T200) (Routine Test).

GAS6 Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q61592.

Mouse

HEK293 Cells

growth arrest-specific 6,Gas-6

Val28-Pro674

> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).