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Anti-CEACAM5 Antibody (1I250) is a Rabbit antibody targeting CEACAM5. Anti-CEACAM5 Antibody (1I250) can be used in WB,ICC/IF,IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-CEACAM5 Antibody (1I250) is a Rabbit antibody targeting CEACAM5. Anti-CEACAM5 Antibody (1I250) can be used in WB,ICC/IF,IHC. |
Synonyms | CEA, CD66e, carcinoembryonic antigen-related cell adhesion molecule 5 |
Ig Type | IgG |
Reactivity | Human |
Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Carcino Embryonic Antigen CEA (CD66e) antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Carcino Embryonic Antigen CEA (CD66e) antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Carcino Embryonic Antigen CEA (CD66e) antibody. Counter stained with hematoxylin. 4. ICC staining Carcino Embryonic Antigen CEA (CD66e) in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining Carcino Embryonic Antigen CEA (CD66e) in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
Application | |
Recommended Dose | WB: 1:500; IHC: 1:50-200; ICC/IF: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The CD66 (carcinoembryonic antigen, CEA, biliary glycoprotein I, BGP-1, CEACAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues. The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. CD66A, CD66B, CD66C, CD66D, CD66E and CD66F are the best characterized CD66 antigens, and CD66A-D expression upregulates on the surface of granulocytes upon stimulation. Certain CD66 family members mediate homotypic and heterotypic intercellular adhesion events. CD66E, also known as CEA, is a well known tumor marker and a heavily glycosylated GPI-linked cell surface molecule. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 76 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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