IL-13 Protein, Mouse, Recombinant (E. coli)

Name: IL-13 Protein, Mouse, Recombinant (E. coli)
Brand: TargetMol
SKU: TMPY-03123U
Price: 851 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: interleukin 13) Copy Product Info

Synonyms: interleukin 13

Catalog No. TMPY-03123U Copy Product Info

IL-13 Protein, Mouse, Recombinant (E. coli) is expressed in E. coli. The accession number is P20109.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$68	-	In Stock
10 µg	$108	7-10 days	7-10 days
20 µg	$177	7-10 days	7-10 days
50 µg	$318	7-10 days	7-10 days
100 µg	$498	7-10 days	7-10 days
200 µg	$851	7-10 days	7-10 days
500 µg	Preferential	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 1.93 ng/ml.
Description	IL-13 Protein, Mouse, Recombinant (E. coli) is expressed in E. coli. The accession number is P20109.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	P20109
Construction	Ser26-Phe131
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20 mM Histidine-HCl, 8% Trehalose, 4% Mannitol, 50 mM NaCl, 0.05% Tween 80, pH 6.0.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	interleukin 13
Research Background	Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13Rα1 with low affinity and triggers association of IL4Rα, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13Rα2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.

Chemical Properties

Molecular Weight

11.7 kDa (Predicted); 9-14 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.