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Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144)

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Catalog No. TMAB-13958

Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144) is a Rabbit antibody targeting Ubiquityl-Histone H2B (Lys120). Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144)

Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144)

😃Good
Catalog No. TMAB-13958
Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144) is a Rabbit antibody targeting Ubiquityl-Histone H2B (Lys120). Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144) is a Rabbit antibody targeting Ubiquityl-Histone H2B (Lys120). Anti-Ubiquityl-Histone H2B (Lys120) Antibody (2R144) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
2R144
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Chromosome.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Ubiquityl-Histone H2B (Lys120)
Antigen Species
Human
Gene Name
H2BC3
Gene ID
Protein Name
Histone H2B type 1-B
Uniprot ID
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Chemical Properties
Molecular WeightTheoretical: 14 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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