IGFBP-3 Protein, Human, Recombinant (His) V2

Name: IGFBP-3 Protein, Human, Recombinant (His) V2
Brand: TargetMol
SKU: TMPY-00835U
Price: 55 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: insulin-like growth factor binding protein 3, IGFBP3, IBP3, BP-53) Copy Product Info

Synonyms: insulin-like growth factor binding protein 3, IGFBP3, IBP3, BP-53

Catalog No. TMPY-00835U Copy Product Info

IGFBP-3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH18962.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$55	-	In Stock
10 µg	$86	-	In Stock
20 µg	$139	7-10 days	7-10 days
50 µg	$269	7-10 days	7-10 days
100 µg	$451	-	In Stock
200 µg	$737	7-10 days	7-10 days
500 µg	$1,400	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Bis-Tris PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human IGFBP-3, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human IGF-II, hFc Tag with the EC50 of 0.19 μg/ml determined by ELISA (QC Test). Human IGFBP-3, His Tag captured on CM5 Chip via anti-his antibody can bind Human IGFI, hFc Tag with an affinity constant of 2.32 nM as determined in SPR assay (Biacore T200).
Description	IGFBP-3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH18962.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	AAH18962
Construction	Gly28-Lys291
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	insulin-like growth factor binding protein 3, IGFBP3, IBP3, BP-53
Research Background	Insulin-like growth factor binding protein-3 (IGFBP-3) is a p53 tumor suppressor-regulated protein and a major carrier for IGFs in circulation. Among six high-affinity IGFBPs, which are IGFBP-1 through 6, IGFBP-3 is the most extensively investigated IGFBP species with respect to its IGF/IGF-I receptor (IGF-IR)-independent biological actions beyond its endocrine/paracrine/autocrine role in modulating IGF action in cancer.

Chemical Properties

Molecular Weight

29.8 kDa (Predicted); 45-60 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.