Immobilized Human SOST, His Tag at 1 μg/ml(100 μl/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 18.6 ng/ml determined by ELISA. (QC Test)
Immobilized Human SOST, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 6.6 ng/ml determined by ELISA.

SOST Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q9BQB4-1.

Human

HEK293 Cells

VBCH,SOST1,sclerostin,DAND6,CDD

Gln24-Tyr213

> 95% as determined by Bis-Tris PAGE

Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.