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Anti-Aconitase 1 Antibody (6P426) is a Rabbit antibody targeting Aconitase 1. Anti-Aconitase 1 Antibody (6P426) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
| Description | Anti-Aconitase 1 Antibody (6P426) is a Rabbit antibody targeting Aconitase 1. Anti-Aconitase 1 Antibody (6P426) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Clone | 6P426 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Bifunctional iron sensor that switches between 2 activities depending on iron availability.Iron deprivation, promotes its mRNA binding activity through which it regulates the expression of genes involved in iron uptake, sequestration and utilization. |
| Immunogen | A synthesized peptide: human Aconitase 1 |
| Antigen Species | Human |
| Gene Name | ACO1 |
| Gene ID | |
| Protein Name | Cytoplasmic aconitate hydratase |
| Uniprot ID | |
| Function | Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding. |
| Molecular Weight | Theoretical: 98 kDa. Actual: 98 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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