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Anti-PLSCR3 Antibody (6F572)

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Catalog No. TMAB-11569 Copy Product Info
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Anti-PLSCR3 Antibody (6F572) is a Rabbit antibody targeting PLSCR3. Anti-PLSCR3 Antibody (6F572) can be used in WB,FCM.
Anti-PLSCR3 Antibody
(6F572)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PLSCR3 Antibody (6F572) is a Rabbit antibody targeting PLSCR3. Anti-PLSCR3 Antibody (6F572) can be used in WB,FCM.
Ig Type
IgG
Clone
6F572
Reactivity
Human (predicted:Mouse,Rat)
Application
Recommended Dose
WB: 1:500-2000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion membrane; Single-pass type II membrane protein.
Tissue SpecificityExpressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundCatalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of the phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer membrane of the mitochondria.Plays an important role in mitochondrial respiratory function, morphology, and apoptotic response.
Antigen Details
Immunogen
A synthesized peptide: human PLSCR3
Antigen Species
Human
Gene Name
PLSCR3
Gene ID
Protein Name
phospholipid scramblase 3
Uniprot ID
Function
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Chemical Properties
Molecular WeightTheoretical: 32 kDa. Actual: 32 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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