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Anti-PLSCR3 Antibody (6F572)

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Catalog No. TMAB-11569

Anti-PLSCR3 Antibody (6F572) is a Rabbit antibody targeting PLSCR3. Anti-PLSCR3 Antibody (6F572) can be used in WB,FCM.

Anti-PLSCR3 Antibody (6F572)

Anti-PLSCR3 Antibody (6F572)

😃Good
Catalog No. TMAB-11569
Anti-PLSCR3 Antibody (6F572) is a Rabbit antibody targeting PLSCR3. Anti-PLSCR3 Antibody (6F572) can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PLSCR3 Antibody (6F572) is a Rabbit antibody targeting PLSCR3. Anti-PLSCR3 Antibody (6F572) can be used in WB,FCM.
Ig Type
IgG
Clone
6F572
Reactivity
Human (predicted:Mouse,Rat)
Application
WB
FCM
Recommended Dose
WB: 1:500-2000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion membrane; Single-pass type II membrane protein.
Tissue SpecificityExpressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundCatalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of the phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer membrane of the mitochondria.Plays an important role in mitochondrial respiratory function, morphology, and apoptotic response.
Antigen Details
Immunogen
A synthesized peptide: human PLSCR3
Antigen Species
Human
Gene Name
PLSCR3
Gene ID
57048
Protein Name
phospholipid scramblase 3
Uniprot ID
Q9NRY6
Function
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Chemical Properties
Molecular WeightTheoretical: 32 kDa. Actual: 32 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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