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Anti-H3-K4-HMTase SETD7 Antibody (3Z594)

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Catalog No. TMAB-06865

Anti-H3-K4-HMTase SETD7 Antibody (3Z594) is a Rabbit antibody targeting H3-K4-HMTase SETD7. Anti-H3-K4-HMTase SETD7 Antibody (3Z594) can be used in WB,IP,FCM.

Anti-H3-K4-HMTase SETD7 Antibody (3Z594)

Anti-H3-K4-HMTase SETD7 Antibody (3Z594)

😃Good
Catalog No. TMAB-06865
Anti-H3-K4-HMTase SETD7 Antibody (3Z594) is a Rabbit antibody targeting H3-K4-HMTase SETD7. Anti-H3-K4-HMTase SETD7 Antibody (3Z594) can be used in WB,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-H3-K4-HMTase SETD7 Antibody (3Z594) is a Rabbit antibody targeting H3-K4-HMTase SETD7. Anti-H3-K4-HMTase SETD7 Antibody (3Z594) can be used in WB,IP,FCM.
Ig Type
IgG
Clone
3Z594
Reactivity
Human,Mouse,Rat
Application
WB
IP
FCM
Recommended Dose
WB: 1:500-2000; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Chromosome (Probable).
Tissue SpecificityWidely expressed. Expressed in pancreatic islets.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundHistone methyltransferase that specifically monomethylates 'Lys-4' of histone H3.H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Antigen Details
Immunogen
A synthesized peptide: human SETD7
Antigen Species
Human
Gene Name
SETD7
Gene ID
80854
Protein Name
Histone-lysine N-methyltransferase SETD7
Uniprot ID
Q8WTS6
Function
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
Chemical Properties
Molecular WeightTheoretical: 41 kDa. Actual: 41 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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