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Anti-AGT Antibody (4U964)

😃Good
Catalog No. TMAH-00039
Alias SERPINA8, Serpin A8, Angiotensinogen, AGT

Anti-AGT Antibody (4U964) is an antibody targeting AGT. Anti-AGT Antibody (4U964) can be used in ELISA, IHC.

Anti-AGT Antibody (4U964)

Anti-AGT Antibody (4U964)

😃Good
Catalog No. TMAH-00039Alias SERPINA8, Serpin A8, Angiotensinogen, AGT
Anti-AGT Antibody (4U964) is an antibody targeting AGT. Anti-AGT Antibody (4U964) can be used in ELISA, IHC.
Pack SizePriceAvailabilityQuantity
50 μL$209 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, IHC

Reactivity: Human
AliasSERPINA8, Serpin A8, Angiotensinogen, AGT
Ig Type
Rabbit IgG
Clone
4U964
Reactivity
Human
Verified Activity
IHC image of TMAH-00039 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Application
ELISA, IHC
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundEssential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. stimulates aldosterone release. is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human Angiotensinogen
Antigen Species
Human
Gene ID
183
Uniprot ID
Biology Area
Cardiovascular, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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