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Anti-SOD2 Antibody (1Y900) (Synonyms: superoxide dismutase 2, mitochondrial, MVCD6, MNSOD, IPOB)

Catalog No. TMAC-03819 Copy Product Info
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Anti-SOD2 Antibody (1Y900) is a Rabbit antibody targeting SOD2. Anti-SOD2 Antibody (1Y900) can be used in IHC,WB.

Anti-SOD2 Antibody (1Y900)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03819
Synonyms superoxide dismutase 2, mitochondrial, MVCD6, MNSOD, IPOB

Anti-SOD2 Antibody (1Y900) is a Rabbit antibody targeting SOD2. Anti-SOD2 Antibody (1Y900) can be used in IHC,WB.

Anti-SOD2 Antibody
(1Y900)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SOD2 Antibody (1Y900) is a Rabbit antibody targeting SOD2. Anti-SOD2 Antibody (1Y900) can be used in IHC,WB.
Synonymssuperoxide dismutase 2, mitochondrial, MVCD6, MNSOD, IPOB
Ig Type
IgG
Clone
1Y900
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of SOD2 on different lysates using anti-SOD2 antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse brain, Lane 2: SH-SY-5Y, Lane 3: Human heart.
2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-SOD2 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe superoxide dismutase family is composed of three metalloenzymes (SOD-1, SOD-2 and SOD-3) that catalyze the oxido-reduction of reactive oxygen species (ROS) such as superoxide anion. The SOD-2 precursor is a 222 amino acid protein that is encoded by nuclear chromatin, synthesized in the cytosol and imported posttranslationally into the mitochondrial matrix. Unlike SOD-1, which is a homodimeric cytosolic Cu-Zn enzyme, SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer??s disease, Parkinson??s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle. Polymorphisms in the SOD-2 gene have also been implicated in nonfamilial, idiopathic, dilated cardiomyopathy in humans.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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