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Anti-LGALS3 Antibody (5J88) is an antibody targeting LGALS3. Anti-LGALS3 Antibody (5J88) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Antibody Type: Recombinant Monoclonal Application: ELISA, WB Reactivity: Human |
Alias | MAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, Galectin3, GALBPCBP35, galactin-3, Gal-3, GAL3, CBP35, AGE-R3 |
Ig Type | hIgG1 |
Clone | 5J88 |
Reactivity | Human |
Verified Activity | Western Blot -Positive WB detected in: PC-3 whole cell lysate, MCF7 whole cell lysate, Hela whole cell lysate, A431 whole cell lysate -All lanes: LGALS3 antibody at 1:1000 -Secondary: Goat polyclonal to human IgG at 1/50000 dilution -Predicted band size: 26 kDa -Observed band size: 26 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:2000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cytoplasm. Nucleus. Secreted. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human LGALS3 Protein |
Antigen Species | Human |
Gene ID | 3958 |
Uniprot ID | |
Biology Area | Neuroscience, Cell biology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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