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Anti-TRIM29 Antibody (4W329)

Catalog No. TMAB-13779 Copy Product Info
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Anti-TRIM29 Antibody (4W329) is a Rabbit antibody targeting TRIM29. Anti-TRIM29 Antibody (4W329) can be used in WB.

Anti-TRIM29 Antibody (4W329)

Copy Product Info
🥰Excellent
Catalog No. TMAB-13779

Anti-TRIM29 Antibody (4W329) is a Rabbit antibody targeting TRIM29. Anti-TRIM29 Antibody (4W329) can be used in WB.

Anti-TRIM29 Antibody
(4W329)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TRIM29 Antibody (4W329) is a Rabbit antibody targeting TRIM29. Anti-TRIM29 Antibody (4W329) can be used in WB.
Ig Type
IgG
Clone
4W329
Reactivity
Human,Mouse,Rat
Verified Activity
Western blot analysis of JAR cell lysate. Using TRIM29 (TMAB-13779) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Colocalizes with intermediate filaments.
Tissue SpecificityExpressed in placenta, prostate and thymus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPlays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.
Antigen Details
Immunogen
A synthesized peptide: human TRIM29
Antigen Species
Human
Gene Name
TRIM29
Gene ID
Protein Name
Tripartite motif-containing protein 29
Uniprot ID
Function
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.
Chemical Properties
Molecular WeightTheoretical: 66 kDa. Actual: 68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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