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Anti-TRIM29 Antibody (4W329)
😃Good
Catalog No. TMAB-13779
Anti-TRIM29 Antibody (4W329) is a Rabbit antibody targeting TRIM29. Anti-TRIM29 Antibody (4W329) can be used in WB.
Anti-TRIM29 Antibody (4W329)
Anti-TRIM29 Antibody (4W329)
😃Good
Catalog No. TMAB-13779
Anti-TRIM29 Antibody (4W329) is a Rabbit antibody targeting TRIM29. Anti-TRIM29 Antibody (4W329) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TRIM29 Antibody (4W329) is a Rabbit antibody targeting TRIM29. Anti-TRIM29 Antibody (4W329) can be used in WB. |
| Ig Type | IgG |
| Clone | 4W329 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Colocalizes with intermediate filaments. |
| Tissue Specificity | Expressed in placenta, prostate and thymus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation. |
| Immunogen | A synthesized peptide: human TRIM29 |
| Antigen Species | Human |
| Gene Name | TRIM29 |
| Gene ID | |
| Protein Name | Tripartite motif-containing protein 29 |
| Uniprot ID | |
| Function | It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. |
| Molecular Weight | Theoretical: 66 kDa. Actual: 68 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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