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Anti-HDAC8 Antibody (7B830)

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Catalog No. TMAB-06945

Anti-HDAC8 Antibody (7B830) is a Rabbit antibody targeting HDAC8. Anti-HDAC8 Antibody (7B830) can be used in WB,ICC/IF,FCM.

Anti-HDAC8 Antibody (7B830)

Anti-HDAC8 Antibody (7B830)

😃Good
Catalog No. TMAB-06945
Anti-HDAC8 Antibody (7B830) is a Rabbit antibody targeting HDAC8. Anti-HDAC8 Antibody (7B830) can be used in WB,ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2627-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HDAC8 Antibody (7B830) is a Rabbit antibody targeting HDAC8. Anti-HDAC8 Antibody (7B830) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
7B830
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Excluded from the nucleoli. Found in the cytoplasm of cells showing smooth muscle differentiation.
Tissue SpecificityWeakly expressed in most tissues. Expressed at higher level in heart, brain, kidney and pancreas and also in liver, lung, placenta, prostate and kidney.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
Antigen Details
Immunogen
A synthesized peptide: human HDAC8
Antigen Species
Human
Gene Name
HDAC8
Gene ID
Protein Name
Histone deacetylase 8
Uniprot ID
Function
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
Chemical Properties
Molecular WeightTheoretical: 42 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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