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GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His)

(Synonyms: GRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, GFR a-like, C6orf144) Copy Product Info

Synonyms: GRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, GFR a-like, C6orf144

Catalog No. TMPK-01706 Copy Product Info
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q6SJE0-1.
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$747-10 days7-10 days
10 µg$1137-10 days7-10 days
20 µg$1757-10 days7-10 days
50 µg$3167-10 days7-10 days
100 µg$4907-10 days7-10 days
200 µg$7937-10 days7-10 days
500 µg$1,4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Mouse GFRAL, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Mouse GDF15, hFc Tag with the EC50 of 2.6 ng/ml determined by ELISA (QC Test).
Description
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q6SJE0-1.
Species
Mouse
Expression System
HEK293 Cells
TagN-His
Accession NumberQ6SJE0-1
ConstructionGln20-Glu350
Protein Purity
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin< 0.1 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsGRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, GFR a-like, C6orf144
Research Background
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
Chemical Properties
Molecular Weight38.3 kDa (Predicted); 47-60 kDa (Reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His) chemical structure | GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His) molecular weight