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Anti-HK1 Antibody (7G677)

(Synonyms: HK1, Hexokinase-A, Hexokinase-1, Hexokinase type I (HK I), Brain form hexokinase) Copy Product Info
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Synonyms: HK1, Hexokinase-A, Hexokinase-1, Hexokinase type I (HK I), Brain form hexokinase

Catalog No. TMAC-01816 Copy Product Info
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Anti-HK1 Antibody (7G677) is a Rabbit antibody targeting HK1. Anti-HK1 Antibody (7G677) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-HK1 Antibody
(7G677)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HK1 Antibody (7G677) is a Rabbit antibody targeting HK1. Anti-HK1 Antibody (7G677) can be used in FCM,ICC/IF,IHC,IP,WB.
SynonymsHK1, Hexokinase-A, Hexokinase-1, Hexokinase type I (HK I), Brain form hexokinase
Ig Type
IgG
Clone
7G677
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose-6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HXK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines. HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues. Of the hexokinases, HXK III has the highest affinity for glucose. Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, determining the ??set point?? for insulin secretion.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 102 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-HK1 Antibody (7G677) molecular weight