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Anti-RNF7 Antibody (6B728)
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Catalog No. TMAB-12328 Copy Product Info
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Anti-RNF7 Antibody (6B728) is a Rabbit antibody targeting . Anti-RNF7 Antibody (6B728) can be used in IHC-P,IHC-F,IF.
Anti-RNF7 Antibody
(6B728)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 µL | $148 | 7-10 days | 7-10 days | |
| 50 µL | $264 | 7-10 days | 7-10 days | |
| 100 µL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-RNF7 Antibody (6B728) is a Rabbit antibody targeting . Anti-RNF7 Antibody (6B728) can be used in IHC-P,IHC-F,IF. |
| Ig Type | IgG |
| Clone | 6B728 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Western blot analysis of HepG2 cell lysate. Using RNF7 (TMAB-12328) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | IHC-P=1:100-200,IHC-F=1:100-200,IF=1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Expressed in heart, liver, skeletal muscle and pancreas. At very low levels expressed in brain, placenta and lung. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription.CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets. |
| Immunogen | A synthesized peptide: human RNF7 |
| Antigen Species | Human |
| Gene Name | RNF7 |
| Gene ID | |
| Protein Name | RING-box protein 2 |
| Uniprot ID | |
| Function | Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents. |
| Molecular Weight | Theoretical: 13 kDa. Actual: 13 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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