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Anti-RNF7 Antibody (6B728)

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Catalog No. TMAB-12328

Anti-RNF7 Antibody (6B728) is a Rabbit antibody targeting RNF7. Anti-RNF7 Antibody (6B728) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.

Anti-RNF7 Antibody (6B728)

Anti-RNF7 Antibody (6B728)

😃Good
Catalog No. TMAB-12328
Anti-RNF7 Antibody (6B728) is a Rabbit antibody targeting RNF7. Anti-RNF7 Antibody (6B728) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-RNF7 Antibody (6B728) is a Rabbit antibody targeting RNF7. Anti-RNF7 Antibody (6B728) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
Clone
6B728
Reactivity
Human,Mouse,Rat
Application
WB
IHC-P
IHC-Fr
ICC/IF
IF
Recommended Dose
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus.
Tissue SpecificityExpressed in heart, liver, skeletal muscle and pancreas. At very low levels expressed in brain, placenta and lung.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundProbable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription.CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets.
Antigen Details
Immunogen
A synthesized peptide: human RNF7
Antigen Species
Human
Gene Name
RNF7
Gene ID
9616
Protein Name
RING-box protein 2
Uniprot ID
Q9UBF6
Function
Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
Chemical Properties
Molecular WeightTheoretical: 13 kDa. Actual: 13 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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