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Anti-Tri-methyl-Histone H4 (Lys20) Antibody (9B476)
Catalog No. TMAB-07141 Copy Product Info
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Anti-Tri-methyl-Histone H4 (Lys20) Antibody (9B476) is a Rabbit antibody targeting Tri-methyl-Histone H4 (Lys20). Anti-Tri-methyl-Histone H4 (Lys20) Antibody (9B476) can be used in WB.
Anti-Tri-methyl-Histone H4 (Lys20) Antibody (9B476)
Copy Product Info🥰Excellent
Catalog No. TMAB-07141
Anti-Tri-methyl-Histone H4 (Lys20) Antibody (9B476) is a Rabbit antibody targeting Tri-methyl-Histone H4 (Lys20). Anti-Tri-methyl-Histone H4 (Lys20) Antibody (9B476) can be used in WB.
Anti-Tri-methyl-Histone H4
(Lys20) Antibody
(9B476)
(Lys20) Antibody
(9B476)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
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| Description | Anti-Tri-methyl-Histone H4 (Lys20) Antibody (9B476) is a Rabbit antibody targeting Tri-methyl-Histone H4 (Lys20). Anti-Tri-methyl-Histone H4 (Lys20) Antibody (9B476) can be used in WB. |
| Ig Type | IgG |
| Clone | 9B476 |
| Reactivity | Human,Mouse |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with Histone H4 (tri methyl K20) monoclonal antibody, unconjugated (TMAB-07141) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated Synthesised methylpeptide: human Histone H4 around the methylation site of tri methyl Lys20 |
| Antigen Species | Human |
| Gene Name | H4C1 |
| Gene ID | |
| Protein Name | Histone H4 |
| Uniprot ID | |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Molecular Weight | Theoretical: 11 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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