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Anti-DAPK1 Antibody (4N343)
😃Good
Catalog No. TMAB-04977
Anti-DAPK1 Antibody (4N343) is a Rabbit antibody targeting DAPK1. Anti-DAPK1 Antibody (4N343) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Anti-DAPK1 Antibody (4N343)
Anti-DAPK1 Antibody (4N343)
😃Good
Catalog No. TMAB-04977
Anti-DAPK1 Antibody (4N343) is a Rabbit antibody targeting DAPK1. Anti-DAPK1 Antibody (4N343) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DAPK1 Antibody (4N343) is a Rabbit antibody targeting DAPK1. Anti-DAPK1 Antibody (4N343) can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| Clone | 4N343 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Colocalizes with the actin filament system. |
| Tissue Specificity | Isoform 2 is expressed in normal intestinal tissue as well as in colorectal carcinomas. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. |
| Immunogen | A synthesized peptide: human DAP kinase 1 |
| Antigen Species | Human |
| Gene Name | DAPK1 |
| Gene ID | |
| Protein Name | Death-associated protein kinase 1 |
| Uniprot ID | |
| Function | Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. |
| Molecular Weight | Theoretical: 160 kDa. Actual: 160 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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