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Anti-DAPK1 Antibody (4N343)
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Catalog No. TMAB-04977 Copy Product Info
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Anti-DAPK1 Antibody (4N343) is a Rabbit antibody targeting DAPK1. Anti-DAPK1 Antibody (4N343) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Anti-DAPK1 Antibody
(4N343)
(4N343)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-DAPK1 Antibody (4N343) is a Rabbit antibody targeting DAPK1. Anti-DAPK1 Antibody (4N343) can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| Clone | 4N343 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Colocalizes with the actin filament system. |
| Tissue Specificity | Isoform 2 is expressed in normal intestinal tissue as well as in colorectal carcinomas. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. |
| Immunogen | A synthesized peptide: human DAP kinase 1 |
| Antigen Species | Human |
| Gene Name | DAPK1 |
| Gene ID | |
| Protein Name | Death-associated protein kinase 1 |
| Uniprot ID | |
| Function | Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. |
| Molecular Weight | Theoretical: 160 kDa. Actual: 160 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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