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Antibody Type: Recombinant Rabbit Monoclonal
Application: IHC-P,IHC-Fr,IP,IF
Reactivity: Human,Mouse,Rat

| Description | Anti-IP3 receptor Antibody (4Z105) is a Rabbit antibody targeting IP3 receptor. Anti-IP3 receptor Antibody (4Z105) can be used in IHC-P,IHC-Fr,IP,IF. |
| Ig Type | IgG |
| Clone | 4Z105 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IP: 1:20-50; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane. |
| Tissue Specificity | Widely expressed. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. |
| Immunogen | A synthesized peptide: human ITPR1 |
| Antigen Species | Human |
| Gene Name | ITPR1 |
| Gene ID | |
| Protein Name | Inositol 1, 4, 5-trisphosphate receptor type 1 |
| Uniprot ID | |
| Function | Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. |
| Molecular Weight | Theoretical: 314 kDa. Actual: 314 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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