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Adiponectin Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is Q15848.

| Pack Size | Price | Availability | Quantity | 
|---|
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. | 
| Description | Adiponectin Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 Cells. The accession number is Q15848. | 
| Species | Human | 
| Expression System | HEK293 Cells | 
| Tag | C-His | 
| Accession Number | Q15848 | 
| Synonyms | GBP28,APM-1,APM1,ADPN,ADIPQTL1,adiponectin, C1Q and collagen domain containing,Adiponectin,ACRP30,ACDC | 
| Construction | Glu19-Asn244 | 
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC | 
| Molecular Weight | 25.6 kDa (Predicted); 30-40 kDa (Due to glycosylation) | 
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. | 
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. | 
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| Research Background | Adiponectin, also known as Acrp30, is an adipocyte-derived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation.Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. | 

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