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Anti-JMJD2A Antibody (6H812)
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Catalog No. TMAB-07871
Anti-JMJD2A Antibody (6H812) is a Rabbit antibody targeting JMJD2A. Anti-JMJD2A Antibody (6H812) can be used in IF, IHC-Fr, IHC-P, IP, WB.
Anti-JMJD2A Antibody (6H812)
Anti-JMJD2A Antibody (6H812)
😃Good
Catalog No. TMAB-07871
Anti-JMJD2A Antibody (6H812) is a Rabbit antibody targeting JMJD2A. Anti-JMJD2A Antibody (6H812) can be used in IF, IHC-Fr, IHC-P, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-JMJD2A Antibody (6H812) is a Rabbit antibody targeting JMJD2A. Anti-JMJD2A Antibody (6H812) can be used in IF, IHC-Fr, IHC-P, IP, WB. |
| Ig Type | IgG |
| Clone | 6H812 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IP: 1:20-50; IF: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Ubiquitous. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. |
| Immunogen | A synthesized peptide: human KDM4A |
| Antigen Species | Human |
| Gene Name | KDM4A |
| Gene ID | |
| Protein Name | Lysine-specific demethylase 4A |
| Uniprot ID | |
| Function | Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.Isoform 2: Crucial for muscle differentiation, promotes transcriptional activation of the Myog gene by directing the removal of repressive chromatin marks at its promoter. Lacks the N-terminal demethylase domain. |
| Molecular Weight | Theoretical: 121 kDa. Actual: 150 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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