SEZ6 Protein, Rat, Recombinant (His)

Name: SEZ6 Protein, Rat, Recombinant (His)
Brand: TargetMol
SKU: TMPK-02013
Rating: 4.5 (1 reviews)

(Synonyms: SEZ-6, SEZ6, BSRP-C, BSRPC) Copy Product Info

Synonyms: SEZ-6, SEZ6, BSRP-C, BSRPC

Catalog No. TMPK-02013 Copy Product Info

SEZ6 Protein, Rat, Recombinant (His) is expressed in HEK293 Cells. The accession number is F1MA42.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$74	7-10 days	7-10 days
10 µg	$113	7-10 days	7-10 days
20 µg	$175	7-10 days	7-10 days
50 µg	$316	7-10 days	7-10 days
100 µg	$490	7-10 days	7-10 days
200 µg	$793	7-10 days	7-10 days
500 µg	$1,470	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	Immobilized Rat SEZ6, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 3.6 ng/ml determined by ELISA (QC Test).
Description	SEZ6 Protein, Rat, Recombinant (His) is expressed in HEK293 Cells. The accession number is F1MA42.
Species	Rat
Expression System	HEK293 Cells
Tag	C-His
Accession Number	F1MA42
Construction	Leu20-His923
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 1 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SEZ-6, SEZ6, BSRP-C, BSRPC
Research Background	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.

Chemical Properties

Molecular Weight

99.62 kDa (Predicted); 170-200 kDa (Reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.