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Anti-HIRA Antibody (2H362) is a Rabbit antibody targeting HIRA. Anti-HIRA Antibody (2H362) can be used in FCM, ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
| Description | Anti-HIRA Antibody (2H362) is a Rabbit antibody targeting HIRA. Anti-HIRA Antibody (2H362) can be used in FCM, ICC/IF. |
| Ig Type | IgG |
| Clone | 2H362 |
| Reactivity | (predicted:Human) |
| Application | |
| Recommended Dose | FCM=1:50-100; ICC/IF=1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Nucleus > PML body. Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence. |
| Tissue Specificity | Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart, liver, lung, and placenta. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. |
| Immunogen | A synthesized peptide: human HIRA |
| Antigen Species | Human |
| Gene Name | HIRA |
| Gene ID | |
| Protein Name | Protein HIRA |
| Uniprot ID | |
| Function | Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. |
| Molecular Weight | Theoretical: 112 kDa. Actual: 112 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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