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Anti-Caspase-7 Antibody (4K535)

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Catalog No. TMAB-03670

Anti-Caspase-7 Antibody (4K535) is a Rabbit antibody targeting Caspase-7. Anti-Caspase-7 Antibody (4K535) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.

Anti-Caspase-7 Antibody (4K535)

Anti-Caspase-7 Antibody (4K535)

😃Good
Catalog No. TMAB-03670
Anti-Caspase-7 Antibody (4K535) is a Rabbit antibody targeting Caspase-7. Anti-Caspase-7 Antibody (4K535) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Caspase-7 Antibody (4K535) is a Rabbit antibody targeting Caspase-7. Anti-Caspase-7 Antibody (4K535) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.
Ig Type
IgG
Clone
4K535
Reactivity
Human
Application
WB
IHC-P
IHC-Fr
IF
FCM
ICC/IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificityHighly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Caspase-7
Antigen Species
Human
Gene Name
CASP7
Gene ID
840
Protein Name
Caspase-7
Uniprot ID
P55210
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
Chemical Properties
Molecular WeightTheoretical: 20/33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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