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Anti-VAMP8 Antibody (3P945) is a Rabbit antibody targeting VAMP8. Anti-VAMP8 Antibody (3P945) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
| Description | Anti-VAMP8 Antibody (3P945) is a Rabbit antibody targeting VAMP8. Anti-VAMP8 Antibody (3P945) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB. |
| Ig Type | IgG |
| Clone | 3P945 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | FCM=1:50-100; ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; IP=1:20-50; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type IV membrane protein. |
| Tissue Specificity | Platelets. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex. |
| Immunogen | A synthesized peptide: human VAMP8 |
| Antigen Species | Human |
| Gene Name | VAMP8 |
| Gene ID | |
| Protein Name | Vesicle-associated membrane protein 8 |
| Uniprot ID | |
| Function | Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. |
| Molecular Weight | Theoretical: 11 kDa. Actual: 15 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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