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Anti-Topoisomerase I Antibody (7M992)
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Catalog No. TMAB-13677
Anti-Topoisomerase I Antibody (7M992) is a Rabbit antibody targeting Topoisomerase I. Anti-Topoisomerase I Antibody (7M992) can be used in WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF.
Anti-Topoisomerase I Antibody (7M992)
Anti-Topoisomerase I Antibody (7M992)
😃Good
Catalog No. TMAB-13677
Anti-Topoisomerase I Antibody (7M992) is a Rabbit antibody targeting Topoisomerase I. Anti-Topoisomerase I Antibody (7M992) can be used in WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Topoisomerase I Antibody (7M992) is a Rabbit antibody targeting Topoisomerase I. Anti-Topoisomerase I Antibody (7M992) can be used in WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 7M992 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus, nucleolus. Nucleus, nucleoplasm. Diffuse nuclear localization with some enrichment in nucleoli. On CPT treatment, cleared from nucleoli into nucleoplasm. Sumolyated forms found in both nucleoplasm and nucleoli. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide: human Topoisomerase 1 |
| Antigen Species | Human |
| Gene Name | TOP1 |
| Gene ID | |
| Protein Name | DNA topoisomerase 1 |
| Uniprot ID | |
| Function | The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. |
| Molecular Weight | Theoretical: 91 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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